Interleukin-6 / IL-6 (Interleucina-6) ELISA Kit Salivar

Os kits da Salimetrics são desenvolvidos e especificamente designados para a pesquisa com SALIVA, e trazem resultados precisos e acurados para os biomarcadores nela presentes.

Kit ELISA designado para a determinação quantitativa de IL-6 (Interleucina-6) em amostras de saliva. 

• Volume de amostra: 60 µL
• Sensibilidade: 0.07 pg/mL
• Tempo de ensaio: 4,5 horas
• Faixa de detecção: 0 - 100 pg/mL
• Testes por unicata: 76
• Testes por duplicata: 38

Referências:

McCarty, M.F. (1999). Interleukin-6 as a central mediator of cardiovascular risk associated with chronic inflammation, smoking, diabetes, and visceral obesity: Down-regulation with essential fatty acids, ethanol and pentoxifylline.  Med Hypotheses, 52(5), 465-77.

Castell, J.V., Gomez-Lechon, M.J., David, M., et al. (1990).  Acute-phase response of human hepatocytes: Regulation of acute-phase protein synthesis by interleukin-6.  Hepatology, 12(5), 1179-86.

Chai, Z., Gatti, S., Toniatti, C., et al. (1996). Interleukin (IL)-6 gene expression in the central nervous system is necessary for fever response to lipopolysaccharide or IL-1β: A study on IL-6-deficient mice.  J Exp Med, 183(1), 311-16.

Tilg, H., Trehu, E., Atkins, M.B. (1994).  Interleukin-6 (IL-6) as an anti-inflammatory cytokine: Induction of circulating IL-1 receptor antagonist and soluble tumor necrosis factor receptor p55.  Blood, 83(1), 113-18.

Sun, D., Emmert-Buck, M.R., Fox, P.C. (1998).  Differential cytokine mRNA expression in human labial minor salivary glands in primary Sjögren’s syndrome.  Autoimmunity, 28(3), 125-37.

Tishler, M., Yaron, I., Shirazi, I., et al. (1999).  Increased salivary interleukin-6 levels in patients with primary Sjögren’s syndrome.  Rheumatol Int, 18(4), 125-27.

Costa, P.P., Trevisan, G.L., Macedo, G.O., et al.  (2010).  Salivary interleukin-6, matrix metalloproteinase-8, and osteoprotegerin in patients with periodontitis and diabetes.  J Periodontology, 81(3), 384-91.

El-Sheikh, M., Buckhalt, J.A., Granger, D.A., et al. (2007).  The association between children’s sleep disruption and salivary interleukin-6.  J Sleep Res, 16(2), 188-97.

Sjögren, E., Leanderson, P., Kristenson, M., Ernerudh, J. (2006).  Interleukin-6 levels in relation to psychosocial factors: Studies on serum, saliva, and in vitro production by blood mononuclear cells.  Brain Behav Immun, 20(3), 270-78.

Groer, M., Murphy, r., bunnell, W., et al. (2010).  Salivary measures of stress and immunity in police officers engaged in simulated critical incident scenarios.  J Occup Environ Med, 52(6), 595-602.

Tanda, N., Ohyama, H., Yamakawa, M., et al. (1998). IL-1β and IL-6 in mouse parotid acinar cells: Characterization of synthesis, storage, and release.  Am J Physiol, 274(1 Pt 1), G147-56.