Melatonin (Melatonina) ELISA Kit Salivar

 Os kits da Salimetrics são desenvolvidos e especificamente designados para a pesquisa com SALIVA, e trazem resultados precisos e acurados para os biomarcadores nela presentes.

 Kit ELISA designado para a determinação quantitativa de Melatonina em amostras de saliva.

• Volume de amostra: 100 µL
• Sensibilidade: 1.37 pg/mL
• Tempo de ensaio: 4 horas
• Faixa de detecção: 0.78 - 50 pg/mL
• Testes por unicata: 76
• Testes por duplicata: 38

Referências:

Claustrat, B., Brun, J., Chazot, G. (2005).  The basic physiology and pathophysiology of melatonin.  Sleep Med Rev, 9(1), 11-24.

Cajochen, C., Kräuchi, K., Wirz-Justice, A. (2003).  Role of melatonin in the regulation of human circadian rhythms and sleep.  J Neuroendocrinol, 15(4), 432-37.

Jou, M.-J., Peng, T.-I., Yu, P.-Z., et al. (2007).  Melatonin protects against common deletion of mitochondrial DNA-augmented mitochondrial oxidative stress and apoptosis.  J Pineal Res, 43(4), 389-403.

Rodriguez, C., Mayo, J.C., Sainz, R.M., et al. (2003).  Regulation of antioxidant enzymes: A significant role for melatonin.  J Pineal Res, 36(1), 1-9.

Gupta, Y.K., Gupta, M., Kohli, K. (2003).  Neuroprotective role of melatonin in oxidative stress vulnerable brain.  Indian J Physiol Pharmacol, 47(4), 373-86.

Kennaway, D.J., Voultsios, A. (1998).  Circadian rhythm of free melatonin in human plasma.  J Clin Endocrinol Metab, 83(3), 1013-15.

Gröschl, M., Köhler, H., Topf, H.G., et al. (2008).  Evaluation of saliva collection devices for the analysis of steroids, peptides and therapeutic drugs.  J Pharm Biomed Anal, 47(3), 478-86.

Voultsios, A., Kennaway, D.J., Dawson, D. (1997).  Salivary melatonin as a circadian phase marker: Validation and comparison to plasma melatonin.  J Biol Rhythms, 12(5), 457-66.

Vakkuri, O. (1985).  Diurnal rhythm of melatonin in human saliva.  Acta Physiol Scand, 124(3), 409-412.

Deacon, S., Arendt, J. (1994).  Posture influences melatonin concentrations in plasma and saliva in humans.  Neurosci Lett, 167(1-2), 191-94.

 Cutando, A., Gómez-Moreno, G., Villalba, J., et al. (2003).  Relationship between salivary melatonin levels and periodontal status in diabetic patients.  J Pineal Res, 35(4), 239-44.