Cotinine (Cotinina) ELISA Kit Salivar

Os kits da Salimetrics são desenvolvidos e especificamente designados para a pesquisa com SALIVA, e trazem resultados precisos e acurados para os biomarcadores nela presentes.

Kit ELISA designado para a determinação quantitativa de Cotinina em amostras de saliva.

• Volume de amostra: 20 µL
• Sensibilidade: 0.15 pg/mL
• Tempo de ensaio: 2,5 horas
• Faixa de detecção: 0.8 - 200 pg/mL
• Testes por unicata: 76
• Testes por duplicata: 38

Referências:

Benowitz, N.L. (1996). Cotinine as a biomarker of environmental tobacco smoke exposure.  Epidemiol Rev, 18(2), 188-204.

Dhar, P. (2004). Measuring tobacco smoke exposure: Quantifying nicotine/cotinine concentration in biological samples by colorimetry, chromatography and immunoassay methods. J Pharm Biomed Anal, 35(1), 155- 68.

Alterman, A.I., Gariti, P., Niedbala, R.S. (2002). Varying results for immunoassay screening kits for cotinine levels. Psychol Addict Behav, 16(3), 256-59.

Van Vunakis, H., Tashkin, D.P., Rigas, B., et al. (1989). Relative sensitivity and specificity of salivary and serum cotinine in identifying tobacco-smoking status of self-reported non-smokers and smokers of tobacco and/or marijuana. Arch Environ  Health, 44(1), 53-58.

Benowitz, N.L., Hukkanen, J., & Jacob, P., 3rd (2009). Nicotine chemistry, metabolism, kinetics and biomarkers.  Handb Exp Pharmacol, 192, 29-60.

Watts, R.R., Longone, J.J., Kinght, G.J., & Lewtas, J. (1990). Cotinine analytical workshop report: Consideration of analytical methods for determining cotinine in human body fluids as a measure of passive exposure to tobacco smoke.  Environ Health Perspect, 84, 173-82.

Roche, D., Callai, F., Reungoat, P., & Momas, I. (2001). Adaptation of an enzyme immunoassay to assess urinary cotinine in nonsmokers exposed to tobacco smoke.  Clin Chem, 47(5), 950-52.

Chard, T. (1990). An introduction to radioimmunoassay and related techniques (4th ed.).  Amsterdam: Elsevier.

Granger, D.A., Blair, C., Willoughby, M., Kivlighan, K.T., Hibel, L.C., Fortunato, C.K., Wiegand, L.E., & The Family Life Project Investigators (2007). Individual differences in salivary cortisol and alpha-amylase in mothers and infants: Relation to tobacco smoke exposure.  Dev Psychobiol, 49(7), 692-701.